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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42199b2770cb0a2fc6d2d17ae6ed76e9e89109db42d4c01539d8a1b20c8bac65' 
  AND token = 'XJCvA9B9lxhWwexVQGRwXlCYdFVAmmc/7vZWvFM9veU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}