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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be4590125d8a16092a7bffede31eb6fae8aeccd355f2afc6863449a670eaced3' 
  AND token = 'EpuRjdUxCSiWUvHS819cVLv/qbn2W+M+8K+kG862kLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}