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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bf33c41d0e8646dc0fafb72bf4dfc43f714938f3cb7a667e881fef727caab31' 
  AND token = 'dCY6HtbKHkJWnmDYvSW/za2WojT72FrPgxrHMq4A2Ro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}