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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3a2ad3d8a704db6dde5ba524ecd201294907a4d9cd6aca3e135f5f241f76012' 
  AND token = 'karWRhLzdT+zvmZs0kiEhhyQJC+NJyc+sMoYYb5PnIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}