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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dee102574256a2f8eff063b5266c0608d858e7ff2b23f746159b15dbbb95f1a4' 
  AND token = 'rEZFdibE+4HLsg86rtVnaxt2rFQIzS4M0CbZrr+9QSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}