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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6990e58f64212daeaa0dce877b95fcbdd5f4ab19f14dc0ac201f26c7c19ff7f0' 
  AND token = 'hY1izitxQq1C/rcR9XonGoW4KdeK9r7a2PI/UHuWuzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}