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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f11cdb5c8c065f5a55411144c66d11f45afe15d2c1c9d697d7a3bd9452c457b' 
  AND token = 'uB4ye0xVOLRhpOgso0G87Tuh4smCCpSFXUbBZ9YuPCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}