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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28fe41e58820e9047f94ab1148eee38a3377320b1b801da99f091d108d97459d' 
  AND token = '+4ur7Hz1uUY9rLjrtRAZWY9vqri8ea49crjarHjAcn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}