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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a15e5f38d548188e5be6e995d5b42fdce712e1d40edc8dea56e3e8435c5d9477' 
  AND token = '0sp+K2gtqOQ3OthjGapP21PFkaL/n1sX7eh8hSN9zxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}