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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dd9c627b0618d22a0e182a3b372a1cd17f18572b8cfed81595189bed9acfa31' 
  AND token = 'rUROsLaGJOfwOCNVslKDa4b7eGf1NXpWLNDEPXaztR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}