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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '495429a7fb94082d147793ae49123dae7dea545c30033f833927c2aa42c13f12' 
  AND token = 'cqJcjz0ER2OYz3KOy8CCHKAa+c4w6zdzsrcM+pVRHLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}