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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1678fb36a53906c354ddebe7323c57c9e288c5e0a728b64b5d0c601bbaf2580a' 
  AND token = 'xDzZbsq6In9X5rX0v2MWAwE5TfKPwgatuzrbVz1nbLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}