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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '201e2a77425661ad41fad6f226182d559253040c7e59411b4749c20131cc78d6' 
  AND token = 'seAybswSOIj9zWfc3zIp0CjfPy+PMI/SiQr3EQLWbiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}