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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f828906f541f0e181cbeada7237fa6dcd8cf77863f87b8c5c960122fda67eec5' 
  AND token = 'L2XJu4bm4/VQYu5BEFRTAi+42VkDk6DSfG0eCL6NEkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}