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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d49d4e1fac1678eaefe01afc2d4af5dc38f3dd96e079693e39242a62e053353' 
  AND token = 'CkTLL84W3zFd+19TI1vmvnoFq8zI9o7Uih4gmqGDWeQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}