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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6249823204dd1ecd40be1c2aac43de27735769a634f6bb032807a1c68b6b5ad1' 
  AND token = 'WquUg1e24kivLe1FJOYo+a53F59+681bwbpmBl8cLE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}