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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf91fd0c107b050b55969fac77b9ed6ec4ef4105c8490220981ee6801243050a' 
  AND token = 'cUao7xvyzGaLURrCwyDinZasBI15x69Ui2mq2MKbzkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}