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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fa1423b92db8a337cb7dc9296b31009e793887a8b481927432c3c5cb30c191a' 
  AND token = 'axBs5kY0iUhB+L362y2IOkFzQKPXToIb3eWut39G+GE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}