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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0e5d4155dc643f8fb87009d210830746f14c9bc057c5fe30d1655a16fd656e1' 
  AND token = 'hTHUO/TCrrfQWEeHMfJ+mHasp2Ia1nv4HyhUw92W7i8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}