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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8326be8cbad3f5d052f8bfb4e776ef4af76266a9503cb80a870611c8c16169c' 
  AND token = 'rHbsV/QGYu84vkdenkuQ/p6iYsl8jh1JoozJK46Tx0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}