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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '422990dd22998677eed68fe5707c3ed2d12d73488cf1b7bd84454138dfa8242f' 
  AND token = 'zyKDw5VaBdc1NtPk4Kh0T9wJ4wC1mBvv9nG8rLctfeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}