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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b6180aff06199f1bc151f444e38193170c6833a7f9fbc3a08ffae1f3a417c86' 
  AND token = 'u0r0KlFNamWUrc1+Te+HjYuetcZyZxx+9XNmftN7Who=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}