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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe71f1f6de3c730534968f398140820fdb2c48f913dce6c4b6124d8f5262b3f7' 
  AND token = 'wOGmQym+1ra/YmC3mW9NPxMrHjQIoL6wkRxzz1E7EAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}