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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbeddb96f8578b811c0289e04e23aebf3a5f69e4a145e69c024383eed6080d7c' 
  AND token = '6hoeG8KysJWRRITPVjDEvStwGOjv+hAzCsMbzfNpiOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}