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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c0062f155b1ddda1d1b4b1c673c5cbb8508b89cccf33e2313b06e79b0410248' 
  AND token = 'jj/GERrjYT1/lxFSuDD8rBQ6IdCAjFX7ww+JHhDiNw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}