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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20159d037df15de652c84578ee71d295a287f2764265951d3704c200f38ef834' 
  AND token = 'GPfoS9JY02SGd0sAJLUIauOIxMk2z9j6UjEE6Hy1Q+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}