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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3574b7d853c885031a67fe772e9c26bc2c7010bc272df0d359cd61bbacb327a0' 
  AND token = 'O+ASl8dJ7yUjH3pQ5AZPII+sS+JMsHhyPgTi5IUm/dg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}