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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '648c4d3df3ef7c48425716f6a8b93684b19c8f5e179a70926c4fe1ebb29ef15d' 
  AND token = 'iRf4EuMf+yawEgyIb9Mh8R/Lx9c3x4Ex8HTtOLDoYCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}