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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3eba7789aea1c9da3d5bbec89afd572c8a01c6bf398e5e8722a15c71326f958e' 
  AND token = 'cOTut7gGILuLfH9rH0Yw8gr+1Mzh5be9c95fMWz+/nA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}