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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edb4615e9501ae27ec7569291400a90fcfcf2522407b6bda08486181202b4cba' 
  AND token = 'S4G9g3vVxbSe3I6xYVhMTITf/7/hWy1b5ghv8AycY/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}