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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c038e633ab31f1cdc2b76d689d19b8022e77d3630b0ed54e88b1f7098375932' 
  AND token = 'D7SHStqbG2t7dQUK4jUSmisDph4sElGzxLwb42sQG2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}