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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e2558b4069d0a32f8dfe6935e090b7291965bcac36d189b47e23fe0b1134c9e' 
  AND token = 'gVA8XjinwaCMnzg2uHs6PcMgHuL//tJaGjaQfteXlrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}