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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdca6150192bc8eea35cbbb2c3f45defbb4362c1331df6a822fd3e105c6d486b' 
  AND token = 'vCAaEw0+Rcx7o23rEZovQkG5wIxRFDbYYJXc7APVanI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}