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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11800c11f5011d76ecb58330b110f4c8d961fe64efab34dce95f91b6982a8e8e' 
  AND token = 'GC/pn4yxY7GTLRhS5dVz1d4z6I9xgWQAeJYcRqbnywU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}