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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '042ea04d41c653467480ebce32dc3cd6c810e33a4e70b0e69da3322510d03780' 
  AND token = '+U1teSzFLkcjmYNgot5Ko/tlE9VrciYGNhrtSQy6Zlk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}