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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad08dd42be26d59b7600754da7723ceb8f473253f43151c14ad691ea836d1dc5' 
  AND token = '5k4kKnau0wOoMUaQWNS4LVXULernubvP+j+zgOPpA+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}