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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50bc7092b98e458869a5a63972ee22735aff750f9478e0d143fa890649037c10' 
  AND token = '9FwAswhlr3gJA/CnNHJv/cbCwHR+adhbw2U16F9LcHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}