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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e3dc99f8551cfd1b251f721435cc513534b4908882baa5201fc1e664579cbbf' 
  AND token = 'CeNAL61pDxoBgZwUZbtyiJHhVL1ATAEKU5BHaUA9AXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}