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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1eef0123d4e5b3947359f0a1d7f78b2a06ef53e1ac2929b5e0212c47e035d341' 
  AND token = 'wry1CUC3DHVkmYXBFo5oI/kgPbEQGfm0MFAJ6S2CxUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}