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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed0b5a2c8e47019dd83c4e7dd2dd270d9c210ede4b0b56af39d51111ae7d3c06' 
  AND token = 'HIdqJJxToCFm4NbzwPPDauLpO9AhwhzBWc0Qv69tSR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}