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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '324aeb9b9e0c8ad5e82607427d293e5953782353b0f0c9d79a3300326645e39c' 
  AND token = '6COszj4cLmjiHWVMD298y83bPd64nwA8AnK7ONmNQ6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}