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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6715744f47b982974a77d129ac96b707c92ca0c9cbf8a3a30b379474a2510d7f' 
  AND token = 'zlBY+dd5/uv/2bRAf+ju+7KHun13BUb5/0ELuB3U/h4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}