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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0ee742920ddadc94108ce3831dc91aa26e284f9a9a00ed56c86eedb93d0c9b9' 
  AND token = 'SQUoLgTuXeYuByiXg5t3L4oJxq1F4aYjrbXOT3zEWjQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}