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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45f6fadc16b36cdc212a036ea764e6a5aa36b8751db3ccb904678fde678e1d1d' 
  AND token = 'TeemhXJxhtup5PJHW++PC4xC7PIBtyReEvxy+GD6USw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}