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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a72e709247fb174ab80d81631a7f60b4ad52d446dee141748d5604513074e8fe' 
  AND token = '5fWkRAvBmRSFy1kJ0aW8luSMj2TrU7unkwLvq4EW6Es=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}