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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9881f7c66cc6c933203a5ac8ff75ce3de6310d55bed989352f59d35ca660e5a9' 
  AND token = 'TLT9TukF6YTjZJocj0akp+2LIUWuID5R2WE4ZsfJML4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}