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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '759b80919ee494a9b05fd54d97f6a3b5be9c4cbc8fc60e2e37e1084c6d9016d0' 
  AND token = 'TS3jpf5IXGLsgK2PVeikq7jYXaiLvC2kATZs5nFnqmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}