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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f588c9cc71ba610c959edbb8de616f083e3639b8483b2ae4bd95c3edc9f0bbdd' 
  AND token = 'hJW/GbJo+6VVWYmbBfvZTwmQXO8s+JbrdyLaBlSgox8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}