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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd905bb23faf4901e7269c072a2354152d650f55360bdb171d1898b0ad77f5aca' 
  AND token = 'OwOTS7yLAiHD0tpKZjk+XIB9zXkGS6iD/N6y0S9d1jA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}