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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb72e80193e0be6d260e6f0b1d49c2cf0b9598c9f9d95007e7830761e6655a5d' 
  AND token = 'bG5ZAiNNTKD70URxwdA+VhTVlZjkTjOLt9rkHpfqdQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}